This study collected detailed data on the practice of coronary artery revascularization at 24 university-affiliated sites in the U.S. from September, 1991 to September 1993. The purpose of this prospective and observational study was to:

• Identify optimal diagnostic, therapeutic, and cost effective approaches to adverse perioperative events;
• Identify the predictors of cardiovascular and neurological outcomes; and
• Assess the impact of gender, ethnicity, and age on surgical outcomes and cost of healthcare resource utilization associated with coronary artery bypass surgery.

The study also evaluated the efficacy of newer intraoperative techniques, such as warm blood cardioplegia, pulmonary artery catheterization, transesophageal echocardiography or specific anti-ischemic cardiac and cerebral therapies, and mechanisms of perioperative ischemia, reperfusion injury and myocardial infarction.

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